Phenolic Composition and Antioxidant Activity of Tanacetum parthenium Cultivated in Different Regions of Ukraine: Insights into the Flavonoids and Hydroxycinnamic Acids Profile

Tanacetum parthenium, also known as feverfew, is rich in bioactive compounds, namely sesquiterpene lactones, flavonoids, and volatile oils. Sesquiterpene lactones possess anti-migraine activity, while phenolic compounds anti-inflammatory antioxidant action. Phytochemical composition determines the pharmacological activity so profiling essential quality assessment. The study aimed to evaluate cultivated feverfew plants’ profiles activity. Eleven were identified samples of Ukraine. Hydroxycinnamic acids predominate quantitative content all samples, chlorogenic acid, 3,5-dicaffeoylquinic 3,4-dicaffeoylquinic acid 4,5-dicaffeoylquinic acid. total flavonoids ranged from 0.8 2.6%; hydroxycinnamic varied 3.3 6.5%. obtained data testify prospects using Ukrainian a raw material with significant substances develop new herbal medicines.